Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method

Diabetes mellitus is a chronic disease in which the body unable to metabolize carbohydrates, fats, and proteins. In this study, eugenol was polymerized then contacted with glucose crosslinked using polyethylene glycol diglycidyl ether (PEGDE). The resulted PE-Glucose-PEGDE eluted ethanol form MIP-Glucose. It characterized by FTIR, SEM, electrodes Eutech 510 potentiostat UV-Vis spectrophotometer. result of polyeugenol synthesis reddish-brown powder yield 99.90% molecular weight 6318.033 g/mol. spectrophotometer analysis showed that 2152.505 ppm. SEM results differences surface morphology material, indicating formation cavities MIP ESM, while no are found NIP ESN. electrode optimization best composition ratio 1 mol: paraffin: graphite, respectively 20:35:45. resulting has Nernst factor 20.24 mV/decade measurement range 10–5–10–1 M, limit detection value 8.363 × 10–5 selectivity coefficient (Kij) (10–5–10–1) M fructose solution 0.3733; 0.23048; 0.17864; 0.12359; 0.1073.